Best Pest Control Spray in 2022 [*Top Picks*]

Looking for the best pest control spray on the market? We’ve got you covered. Check out our ratings of absolute bestsellers below and make a final decision.

7766 Reviews Scanned

  • Ortho Home Defense Insect Killer for Indoor & Perimeter2: With Comfort Wand, Kills Ants, Cockroaches, Spiders, Fleas & Ticks, Odor Free, 1.1 gal.
    Bestseller #1
    Ortho Home Defense Insect Killer for Indoor & Perimeter2: With Comfort Wand, Kills Ants, Cockroaches, Spiders, Fleas & Ticks, Odor Free, 1.1 gal. (386)
      Ortho Home Defense Insect Killer for Indoor & Perimeter2 with Comfort Wand kills ants, cockroaches, spiders, fleas, ticks and other listed bugs; the formula is odor free, won't stain, and keeps listed bugs out KILLS BUGS INSIDE: Kills those annoying home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, beetles, silverfish, centipedes and millipedes KEEPS BUGS OUTSIDE: Creates a bug barrier that will kill bugs you have and prevents new bugs for up to 12 months (applies to ants, roaches and spiders indoors on non-porous surfaces) NO STAINING OR STINK: This spray can be used indoors and out, leaves no residue, and has no odor; people and pets may re-enter treated areas after spray has dried WAND MAKES APPLICATION EASY: The Comfort Wand eliminates hand fatigue, and there's no pumping required, making it easy to spray along your home's perimeter--indoors and outside
  • Wondercide Natural Products - Indoor Pest Control Spray for Home and Kitchen - Fly, Ant, Spider, Roach, Flea, Bug Killer and Insect Repellent - Eco-Friendly, Pet and Family Safe — 32 oz Lemongrass
    Bestseller #1
    Wondercide Natural Products - Indoor Pest Control Spray for Home and Kitchen - Fly, Ant, Spider, Roach, Flea, Bug Killer and Insect Repellent - Eco-Friendly, Pet and Family Safe — 32 oz Lemongrass (1653)
      KILLS & REPELS. A preventative and a treatment, this pet-safe insect spray kills and repels indoor pests and keeps your home pest-free. Kills flying, crawling, biting and stinging pests including ants, roaches, spiders, flies, fleas, ticks, wasps, scorpions, mosquitoes, fruit flies, silverfish, moths, gnats, carpet beetles, earwigs, palmetto bugs, waterbugs. PROTECT YOUR HOME. This versatile bug control spray is also an indoor flea treatment and flea killer for your home. It kills fleas in carpet, furniture, bedding and flooring, and eliminates adults, eggs, and larvae in the home without staining. SAFE FOR DOGS & CATS. Pet-friendly, this spray is gentle enough to use several times a week around your loved ones, throughout the house, yet powerful enough to fully eliminate pests and provide lasting defense of your household from invading insects. PLANT-BASED AND POWERFULLY EFFECTIVE. Using natural essential oils, this spray is a safe alternative to electronic bug zappers, lights, traps, powders, granules and conventional pesticides. No artificial colors, fragrances or harsh chemicals. Biodegradable. Cruelty-Free. EASY-TO-USE. This eco-friendly biopesticide can be sprayed easily around the home, throughout the kitchen, bathroom, and any other living areas. Simply spray around windows, doors, baseboards, under sinks, in cabinets, and around appliances. Works great for dog kennels and cat condos, too! Spray as often as desired for a pest-free home. Made in the USA from naturally-derived ingredients and safe around children. Safe when used as directed.
  • Ortho Home Defense Max Indoor Insect Barrier: Starts to Kill Ants, Roaches, Spiders, Fleas & Ticks Fast, 1 gal.
    Bestseller #1
    Ortho Home Defense Max Indoor Insect Barrier: Starts to Kill Ants, Roaches, Spiders, Fleas & Ticks Fast, 1 gal. (386)
      Ortho Home Defense Max Indoor Insect Barrier kills and prevents insects inside your home (12-month control for ants, roaches & spiders indoors on non-porous surfaces) KILL LISTED INSECTS FAST: Kills all common household bugs like ants, cockroaches, spiders, fleas, ticks, scorpions, beetles, earwigs, silverfish, centipedes, millipedes, and other listed insects INDOOR USE: Apply wherever insects are: in kitchens, bathrooms, basements, around doors and windows; spray the hard to reach places where bugs are a recurring problem USE WITH CONFIDENCE: Dries up to 30% faster (vs. other Ortho formulas) and leaves no stains or fumes; people and pets may enter treated areas after spray has dried EASY TO APPLY: Extended Reach Comfort Wand, now with 2X the reach (vs. other Ortho Comfort Wands) helps reduce back bending and hand fatigue with its one-touch continuous stream delivery — no pumping required
  • Mighty Mint Gallon (128 oz) Insect and Pest Control Peppermint Oil - Natural Spray for Spiders, Ants, and More - Non Toxic
    Bestseller #1
    Mighty Mint Gallon (128 oz) Insect and Pest Control Peppermint Oil - Natural Spray for Spiders, Ants, and More - Non Toxic (2098)
      Safe Extra Concentrated for Long-Lasting Protection Natural Ingredients Proven Effective in the Real World Large 1 Gallon Container Powerful Essential Oil
  • Wondercide - EcoTreat Ready-to-Use Outdoor Pest Control Spray with Natural Essential Oils - Mosquito and Insect Repellent, Treatment, and Killer - Plant-Based - Safe for Pets, Plants, Kids - 32 oz
    Bestseller #1
    Wondercide - EcoTreat Ready-to-Use Outdoor Pest Control Spray with Natural Essential Oils - Mosquito and Insect Repellent, Treatment, and Killer - Plant-Based - Safe for Pets, Plants, Kids - 32 oz (1653)
      KILLS & REPELS. A preventative and a treatment, this spray is a natural pest repellent, and kills mosquitoes, ants, fleas, ticks, roaches, flies, scorpions, chiggers, crickets, chinch bugs, japanese beetles, no-see-ums, gnats and more. Safe alternative to conventional pesticide sprays, baits, ant granules, zappers or foggers. SPRAY & PLAY! Safe around cats, dogs and people of all ages, with no wait time for drying or reentry into sprayed outside areas. Just attach directly to a garden hose, spray your backyard, and enjoy. Keep the bottle & Refill the sprayer with our Outdoor Pest Control Concentrate! TREATS UP TO 5,000 SQUARE FEET. A bug control spray that can be safely used on lawns, gardens, grass, picnic areas, playgrounds, patios, vegetables, flowers, siding, brick, paint and more. Treat an existing pest infestation or for prevention. Application coverage depends on water pressure and walking speed. NO HARSH CHEMICALS. No artificial colors, fragrances or harsh pesticides. Made in the USA from powerful, sustainable plant-based ingredients. Cruelty free and biodegradable. Keep the bottle & Refill the sprayer with our Outdoor Pest Control Concentrate! POWERED BY NATURE, AS POWERFUL AS PERMETHRIN. Powered by cedar oil, our eco-friendly formula is proven to kill and repel pests. Safe when sprayed outdoors around pets, kids, and beneficial insects like bees and butterflies. Permethrin-Free. Packaging may vary.
  • EcoSmart Natural, Plant-Based Indoor/Outdoor Home Pest Control, 24 Ounce Ready-to-Spray Bottle
    Bestseller #1
    EcoSmart Natural, Plant-Based Indoor/Outdoor Home Pest Control, 24 Ounce Ready-to-Spray Bottle (11538)
      FRESH SCENT: EcoSmart's Natural Indoor/Outdoor Home Pest Control eliminates ants, roaches, crickets, ticks and other household pests by contact with the help of essential oils, such as Rosemary, Clove and Thyme, so there's no overbearing, harsh, chemical smell- only a fresh scent and no bugs ENVIRONMENTALLY FRIENDLY: Our natural, plant-based formula kills home pests without harming fish, wildlife and does not contaminate groundwater supplies, so you can feel good about using EcoSmart CHILD AND PET FRIENDLY: Safe to use around children and pets (when used as directed) NO CHEMICAL: Take chemicals out of your lawn, garden and home equation with EcoSmart MADE IN THE USA
  • Mighty Mint - 16oz Insect and Pest Control Peppermint Oil - Natural Spray for Spiders, Ants, and More - Non Toxic
    Bestseller #1
    Mighty Mint - 16oz Insect and Pest Control Peppermint Oil - Natural Spray for Spiders, Ants, and More - Non Toxic (2098)
      Safe Extra Concentrated for Long-Lasting Protection Natural Ingredients Proven Effective in the Real World Large 16oz Bottle Powerful Essential Oil
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